calpain inhibitor-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T38931	Calpain Inhibitor-1
	Calpain Inhibitor-1 (compound 36) is a highly potent and selective inhibitor of Calpain 1 (Cal1), which is a cysteine protease. It exhibits an IC50 value of 100 nM and a Ki value of 2.89 μM.
T6583	MG-101	ALLN,Ac-LLnL-CHO,Calpain inhibitor I,Calpain inhibitor-1,MG101	Cysteine Protease , Proteasome
	MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.		Cysteine Protease , Proteasome
T9710	Dazcapistat		Cysteine Protease
	Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively.		Cysteine Protease
T2493	PD 151746		Cysteine Protease , Proteasome
	PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). Its IC50 values are 0.26 ± 0.03 μM (Ki for μ-calpain) and 5.33 ± 0.77 μM (Ki for m-calp...		Cysteine Protease , Proteasome
T14187	ALLM	Calpain inhibitor II	Others
	ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].		Others
T63708	Calpain-2-IN-1
	Calpain-2-IN-1 is a selective calpain-2 inhibitor that prolongs ERK activation and thus enhances learning and memory.
T80103	Z-Leu-Tyr-Chloromethylketone
	Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor [1].
T72439	Calpain Inhibitor XI
	Calpain Inhibitor XI, a reversible covalent inhibitor of calpain-1, is utilized in the research of neurodegenerative disorders.
T80551	Calpain inhibitor V	Mu-Val-HPh-FMK	Antibiotic
	Calpain Inhibitor V (Mu-Val-HPh-FMK) is a cell-permeable, irreversible calpain inhibitor with demonstrated anti-chlamydial activity [1].		Antibiotic
T13486	Neurodegenerative Disorder-Targeting Compound 1		Others
	Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].		Others
T28786	SJA6017	SJA-6017,Calpain Inhibitor VI,Calpain-In-4,SJA 6017,Calpain Inhibitor 4
	SJA6017 is a inhibitor of calpain-1 (IC50 = 7.5 nM) and calpain-2 ( IC50 = 78 nM). SJA6017 also inhibits cathepsins B (IC50s = 15 nM) and cathepsins L (IC50s = 1.6 nM). SJA6017 reduces apoptotic cell death, preserves spi...
T83527	(Rac)-Neurodegenerative Disorder-Targeting Compound 1
	(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.
T21949	Calpain Inhibitor XII
	(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor targeting calpain I (μ-calpain) with a Ki value of 19 nM. It exhibits lower affinities for calpain II (m-calpain, Ki=120 nM) and cathepsin B (Ki=750 nM)...
T78632	Z-LLY-FMK	Calpain Inhibitor IV	Proteasome
	Z-LLY-FMK (Calpain Inhibitor IV) serves as an inhibitor of calpain, a family of proteases implicated in the apoptosis of various cell systems. Specifically, this compound suppresses intestinal cell apoptosis following co...		Proteasome
T75794	Acetyl-Calpastatin(184-210)(human) TFA
	Acetyl-Calpastatin(184-210)(human) TFA, a potent, selective, and reversible inhibitor of calpain, demonstrates Ki values of 0.2 nM for µ-calpain and 6 μM for cathepsin L, indicating high specificity and efficacy in inhib...
T76364	Ac-Leu-Leu-Norleucinol
	Ac-Leu-Leu-Norleucinol (ALLN), a calpain inhibitor, is employed in the research of Acetaminophen-induced acute liver damage. It effectively reduces levels of glutamic-oxalacetic transaminase (ALT) and glutamic-pyruvic tr...